The index closed down 1.17 per cent or 60.10 points to 5,079.27.
Yet again, the index was mirroring activity in New York.
While the Dow started firmly, it dropped at 10:00 EDT.
At 11:38 EDT (16:38 BST) the index was down 0.56 per cent to 9,694.06.
The S&P 500 in Chicago dropped close to one per cent.
Leading the gains in London was Autonomy up 3.01 per cent on rumours of a takeover bid from Microsoft.
Insurer Old Mutual gained 2.61 per cent, Carnival gained 2.35 per cent, Intertek rose 2.09 per cent and British Sky Broadcasting climbed 0.99 per cent.
Heading the drops was Wolseley down 4.46 per cent.
British Airways fell 4.31 per cent, Land Securities lost 3.85 per cent, Rexam slid 3.86 per cent and Hammerson lost 3.86 per cent.
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